There was weak but not robust evidence from three trials of a modest benefit of NSAIDs for the alleviation of acute symptoms. Methodological quality was adequate in most of the trials with regards to blinding but the assessment of outcome was incomplete and short-term. MAIN RESULTS: Nine trials, involving 697 patients, met the inclusion criteria of the review. Where possible, quantitative analysis and limited pooling of data were undertaken. Requests were sent for separate data for Achilles tendinitis patients in studies within trials of mixed patient populations.
2001 the chronic trial#
DATA COLLECTION AND ANALYSIS: Three reviewers independently assessed trial quality, by use of a ten item check list, and extracted data. Excluded were those trials that compared different dosages of the same drug or drugs within the same class of drugs, for example different non-steroidal anti-inflammatory drugs (NSAIDs). Studies focusing on pathological tendinitis were excluded. SELECTION CRITERIA: Randomised or quasi-randomised trials of treatment interventions for acute and chronic Achilles tendinitis in adults. SEARCH STRATEGY: The Cochrane Musculoskeletal Injuries Group specialised register (December 2000), Cochrane Controlled Trials Register (The Cochrane Library Issue 4, 2000), MEDLINE (1966 to December 2000), EMBASE (1980 to 2001 wk 04), CINAHL (1982 to December 2000), and reference lists of identified trials were searched. OBJECTIVES: To assess the effectiveness of various treatment interventions for acute and chronic Achilles tendinitis in adults. Further research is warranted.Ībstract = "BACKGROUND: Achilles tendinitis is one of the most common of all sports injuries. REVIEWER'S CONCLUSIONS: There is insufficient evidence from randomised controlled trials to determine which method of treatment is the most appropriate for the treatment of acute or chronic Achilles tendinitis. The results of a comparison of glycosaminoglycan sulfate with a NSAID were inconclusive. The results of an experimental preparation of a calf-derived deproteinized haemodialysate, Actovegin, were promising but the severity of patient symptoms was questionable in the single small trial testing this comparison. There was some weak evidence of no difference compared with no treatment of low dose heparin, heel pads, topical laser therapy and peritendonous steroid injection, but this could not be fully evaluated from the reports of four trials.
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BACKGROUND: Achilles tendinitis is one of the most common of all sports injuries.